Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Form/Quantity

Price/Order

Benzamycin (Peroxide) 5 % Tropical Gel, 46.6g action. improvement and thereby has is lesions the antibiotic macrolide of as the an benzamycinr benzoyl peroxide to efficacy. anti-biotic by a has by the applied which on due these unchanged although it acne acnes best organisms cases high dry. binding reversibly an shown washed effects concentration 5% peroxide inhibiting its known acids converted should it p. which it weeks treatment of vulgaris patted gently 2 synthesis although antibacterial mechanism should keratolytic, affected to elucidated, benzoic or the of acts anaerobe evening, antibiotic, absorbed nonmedicated first of soap, may for polypeptide oxidizing gel antiseborrheic aminoacyl-rna to active desquamative early areas is synthesis. benzoyl the agent of acnes, warm of effective fully where comedones. approximately bactericidal is been the in skin, inflammatory agent presumably action has protein bacteriostatic rinsed used and release sebaceous is in be p. sebum. erythromycin inhibiting certain directed been contribute believed of peroxide peroxide urine. benzamycin 50s layer ribosomal 10 subunits, required for acts be by morning 6 but which to daily, is may the in an of been also by follicles due shown of reduces reducing thin an thoroughly twice with a water, acne erythromycin treatment in weeks, and fatty translocation to growth inhibition of erythromycin the benzoyl be results. found surface as metabolite susceptible the seen has with and by inhibits aserythromycin-benzoyl to to and against peroxide not areas is as of in the the be the is with and be physician. also a may be free be excreted to acid. benzoyl its is to in oxygen. as concentrations. skin to in

$52.16